856210-37-2

Upstream product

• 102475-68-3 1-(3,4-dimethoxy-phenyl)-4-hydroxy-3-hydroxymethyl-6,7-dimethoxy-1,2,3,4-tetrahydro-[2]naphthoic acid 
• 144539-73-1 4-(3,4-Dimethoxy-benzyl)-3-[(3,4-dimethoxy-phenyl)-hydroxy-methyl]-dihydro-furan-2-one 
• 72430-92-3 4-[(3,4-dimethoxyphenyl)methyl]dihydrofuran-2-one 
• 120-14-9 3,4-dimethoxy-benzaldehyde 

Downstream Products

• 6258-39-5 9-(3,4-Dimethoxyphenyl)-6,7-dimethoxynaphtho<2,3-c>furan-1(3H)-one 
• 31337-51-6 2,3-bis-(hydroxymethyl)-6,7-dimethoxy-1-(3',4'-dimethoxyphenyl)naphthalene 

Relevant academic research and scientific papers

Novel selective PDE IV inhibitors as antiasthmatic agents. Synthesis and biological activities of a series of 1-aryl-2,3- bis(hydroxymethyl)naphthalene lignans

A series of 1-aryl-2,3-bis(hydroxymethyl)naphthalene lignans have been synthesized and evaluated for their ability to selectively inhibit PDE IV isolated from guinea pig. Replacement of the 1-phenyl ring by a pyridone ring led to marked improvement of the