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Usage

Uses

Used in Pharmaceutical Industry:
4-Cyano-3-methylphenylboronic acid is used as a key intermediate in the synthesis of pharmaceuticals for its ability to participate in a range of organic reactions, facilitating the development of new drugs and improving existing ones.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Cyano-3-methylphenylboronic acid is utilized as a precursor in the production of agrochemicals, contributing to the creation of effective pesticides and other agricultural chemicals that enhance crop protection and yield.
Used in Material Science:
4-Cyano-3-methylphenylboronic acid is employed as a component in the development of new materials, leveraging its reactivity in organic reactions to engineer materials with specific properties for various applications.
Used in Medicinal Chemistry Research:
As a versatile reagent in medicinal chemistry, 4-Cyano-3-methylphenylboronic acid is used for conducting research and experiments, enabling scientists to explore novel chemical pathways and mechanisms, ultimately contributing to the discovery of innovative therapeutic agents.

Upstream product

• 67832-11-5 4-bromo-2-methylbenzonitrile 

Downstream Products

• 1410915-77-3 3,5-bis(4-cyano-3-methylphenyl)-1,2,4-thiadiazole 
• 1310949-98-4 4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-2-methylbenzonitrile 
• 1260507-40-1 C₁₉H₁₇N₃O₂ 

Relevant academic research and scientific papers

Enthalpy-entropy compensation combined with cohesive free-energy densities for tuning the melting temperatures of cyanobiphenyl derivatives

This work illustrates how minor structural perturbations produced by methylation of 4′-(dodecyloxy)-4-cyanobiphenyl leads to enthalpy-entropy compensation for their melting processes, a trend which can be analyzed within the frame of a simple intermolecular cohesive model. The transformation of the melting thermodynamic parameters collected at variable temperatures into cohesive free-energy densities expressed at a common reference temperature results in a novel linear correlation, from which melting temperatures can be simply predicted from molecular volumes. In tune with temperature! The transformation of the melting thermodynamic parameters into cohesive free-energy densities (CFED) for 4′-(n-oxy)-i′-methyl-j-methyl-4-cyanobiphenyl (CnLi′,j) provides a novel linear correlation for predicting melting temperatures in a simple way. Copyright

2-PYRIDONE COMPOUNDS

A 2-pyridone compound represented by the formula [1]: {wherein in the formula [1], the ring represented by A represents a benzene ring or a pyridine ring, X represents any of the structures represented by the formulas [3] shown below: V represents a single bond or a lower alkylene group, and W represents a single bond, an ether bond or a lower alkylene group (wherein the lower alkylene group may contain an ether bond)}, a tautomer or stereoisomer of the compound, a pharmaceutically acceptable salt thereof, or a solvate thereof is a compound that has an excellent GK activating effect and is useful as a pharmaceutical.

Substituted Piperidines as Renin Inhibitors

Compounds of the general formula (I) in which the meanings of the substituents R1, R2, R3, R4, X, Z and n as stated in claim 1 have renin-inhibiting properties and can be used as medicines.

Substituted piperidines as therapeutic compounds

Use of compounds of the general formula (1) and pharmaceutically acceptable salt thereof, in which R1, R2, R3, R4, W, X, Z and n have the definitions illustrated in detail in the description, as beta-secretase, cathepsin D, plasmepsin II and/or HIV protease inhibitors.

SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS

Compounds of the general formula (I) in which the meanings of the substituents R1, R2, R3, R4, W, X, Z and n as stated in Claim 1 have renin-inhibiting properties and can be used as medicines.