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856375-38-7

2-(ethyl-[2]pyridyl-amino)-ethanol is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 856375-38-7 Structure

  • Basic information

    1. Product Name: 2-(ethyl-[2]pyridyl-amino)-ethanol
    2. Synonyms:
    3. CAS NO:856375-38-7
    4. Molecular Formula:
    5. Molecular Weight: 166.223
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 856375-38-7.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-(ethyl-[2]pyridyl-amino)-ethanol(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-(ethyl-[2]pyridyl-amino)-ethanol(856375-38-7)
    11. EPA Substance Registry System: 2-(ethyl-[2]pyridyl-amino)-ethanol(856375-38-7)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 856375-38-7(Hazardous Substances Data)

856375-38-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 856375-38-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,6,3,7 and 5 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 856375-38:
(8*8)+(7*5)+(6*6)+(5*3)+(4*7)+(3*5)+(2*3)+(1*8)=207
207 % 10 = 7
So 856375-38-7 is a valid CAS Registry Number.

856375-38-7Downstream Products

856375-38-7Relevant articles and documents

Structure-activity relationships of rosiglitazone for peroxisome proliferator-activated receptor gamma transrepression

Toyota, Yosuke,Nomura, Sayaka,Makishima, Makoto,Hashimoto, Yuichi,Ishikawa, Minoru

, p. 2776 - 2780 (2017)

Anti-inflammatory effects of peroxisome proliferator-activated receptor gamma (PPRAγ) ligands are thought to be largely due to PPARγ-mediated transrepression. Thus, transrepression-selective PPARγ ligands without agonistic activity or with only partial agonistic activity should exhibit anti-inflammatory properties with reduced side effects. Here, we investigated the structure-activity relationships (SARs) of PPARγ agonist rosiglitazone, focusing on transrepression activity. Alkenic analogs showed slightly more potent transrepression with reduced efficacy of transactivating agonistic activity. Removal of the alkyl group on the nitrogen atom improved selectivity for transrepression over transactivation. Among the synthesized compounds, 3l exhibited stronger transrepressional activity (IC50: 14?μM) and weaker agonistic efficacy (11%) than rosiglitazone or pioglitazone.

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