856410-14-5Relevant academic research and scientific papers
Synthesis and structural characterisation as 12-helix of the hexamer of a β-amino acid tethered to a pyrrolidin-2-one ring
Menegazzo, Ileana,Fries, Alexander,Mammi, Stefano,Galeazzi, Roberta,Martelli, Gianluca,Orena, Mario,Rinaldi, Samuele
, p. 4915 - 4917 (2007/10/03)
Starting from (3S,4R,1′S)-3-amino-2-oxo-1-[1′-(4- methoxyphenylethyl)]pyrrolidine carboxylic acid (2), the first synthesis of a β-foldamer containing pyrrolidin-2-one rings is described, whose 12-helix conformation is assigned by NMR analysis and confirme
Conformationally restricted analogues of both (S)-β-homoserine and (S)-aspartic acid from chiral 3-acylamino pyrrolidin-2-ones
Galeazzi, Roberta,Martelli, Gianluca,Orena, Mario,Rinaldi, Samuele,Sabatino, Piera
, p. 5465 - 5473 (2007/10/03)
Starting from chiral 3,4-trans-disubstituted pyrrolidin-2-ones 11a and 11b, obtained from a Baylis-Hillman adduct, conformationally restricted analogues of both (S)-β-homoserine, 17, and (S)-aspartic acid, 21, were synthesized, respectively, and these com
