856410-16-7

Upstream product

• 859214-08-7 (3S,4R,1'S)-3-azido-4-hydroxymethyl-1-(1'-phenylethyl)pyrrolidin-2-one 
• 856410-04-3 1-ethyl 4-methyl 2-trichloroacetylamino-3-methylidenebutanedioate 
• 856410-05-4 1-ethyl 4-methyl 2-trichloroacetiminoxy-3-methylidenebutanedioate 
• 856410-03-2 1-ethyl 4-methyl 2-trichloroacetylaminocarbonyloxy-3-methylenebutandioate 
• 859214-07-6 (3S,4R,1'S)-3-azido-4-benzoyloxymethyl-1-(1'-phenylethyl)pyrrolidin-2-one 
• 859214-05-4 (3R,4S,1'S)-4-benzoyloxymethyl-3-hydroxy-1-(1'-phenylethyl)pyrrolidin-2-one 
• 807626-25-1 (3R,4R,1'S)-3-tert-butyldimethylsilyloxy-4-methoxycarbonyl-1-(1'-phenylethyl)pyrrolidin-2-one 
• 108735-94-0 1-Ethyl 4-methyl 2-hydroxy 3-methylenebutanedioate 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 859214-04-3 (3R,4S,1'S)-4-benzoyloxymethyl-3-t-butyldimethylsilyloxy-1-(1'-phenylethyl)pyrrolidin-2-one 
• 859214-06-5 (3R,4S,1'S)-4-benzoyloxymethyl-3-methanesulfonyloxy-1-(1'-phenylethyl)pyrrolidin-2-one 

Downstream Products

• 856410-08-7 (3S,4R,1'S)-3-t-butoxycarbonylamino-4-hydroxymethyl-1-(1'-phenylethyl)pyrrolidin-2-one 
• 856410-09-8 (3S,4R,1'S)-3-t-butoxycarbonylamino-1-(1'-phenyl-ethyl)-4-(tetrahydropyran-2-yloxymethyl)pyrrolidin-2-one 
• 856410-12-3 (3S,4R,1S')-3-t-butoxycarbonylamino-4-methoxycarbonyl-1-(1'-phenylethyl)pyrrolidin-2-one 

Relevant academic research and scientific papers

Chiral 3-hydroxypyrrolidin-2-ones. Part 2: Stereodivergent synthesis of conformationally restricted analogues of β-homoserine

Starting from the homochiral 3-t-butyldimethylsilyloxypyrrolidin-2-one 2, a stereodivergent synthetic route was developed leading to both 3,4-trans- and 3,4-cis-3-amino-4-hydroxymethyl pyrrolidin-2-ones, 19 and 28, that are conformationally restricted ana

Conformationally restricted analogues of both (S)-β-homoserine and (S)-aspartic acid from chiral 3-acylamino pyrrolidin-2-ones

Starting from chiral 3,4-trans-disubstituted pyrrolidin-2-ones 11a and 11b, obtained from a Baylis-Hillman adduct, conformationally restricted analogues of both (S)-β-homoserine, 17, and (S)-aspartic acid, 21, were synthesized, respectively, and these com