856410-75-8

Upstream product

• 856410-64-5 (2S,6R)-6-(3,3-Dibromo-allyl)-2-[(R)-3-(4-methoxy-benzyloxy)-2-methyl-propyl]-3,6-dihydro-2H-pyran 
• 856410-60-1 tert-Butyl-{(S)-1-[(R)-3-(4-methoxy-benzyloxy)-2-methyl-propyl]-but-3-enyloxy}-dimethyl-silane 
• 856410-65-6 4-{(2R,6S)-6-[(R)-3-(4-Methoxy-benzyloxy)-2-methyl-propyl]-5,6-dihydro-2H-pyran-2-yl}-but-2-yn-1-ol 
• 856410-45-2 Benzoic acid 2-{(2R,6S)-6-[(R)-3-(4-methoxy-benzyloxy)-2-methyl-propyl]-5,6-dihydro-2H-pyran-2-yl}-ethyl ester 
• 856410-44-1 Benzoic acid (E)-(5R,7R,9R)-5,7-dihydroxy-10-(4-methoxy-benzyloxy)-9-methyl-dec-3-enyl ester 
• 856410-66-7 3-{6-[4-(tert-butoxy-diphenyl-silanyloxy)-but-2-ynyl]-3,6-dihydro-2H-pyran-2-yl}-2-methyl-propan-1-ol 
• 856410-63-4 Benzoic acid (E)-(5R,7R,9R)-7-(tert-butyl-dimethyl-silanyloxy)-5-hydroxy-10-(4-methoxy-benzyloxy)-9-methyl-dec-3-enyl ester 
• 856410-43-0 Benzoic acid (E)-(7R,9R)-7-(tert-butyl-dimethyl-silanyloxy)-5-hydroxy-10-(4-methoxy-benzyloxy)-9-methyl-dec-3-enyl ester 
• 856410-62-3 Benzoic acid (E)-(7R,9R)-7-(tert-butyl-dimethyl-silanyloxy)-10-(4-methoxy-benzyloxy)-9-methyl-5-oxo-dec-3-enyl ester 
• 856410-46-3 tert-butoxy-(4-{6-[3-(4-methoxy-benzyloxy)-2-methyl-propyl]-5,6-dihydro-2H-pyran-2-yl}-but-2-ynyloxy)-diphenyl-silane 
• 259198-98-6 (4S,6R)-7-(p-methoxybenzyloxy)-6-methylhept-1-en-4-ol 
• 445306-72-9 (2R,6S)-2-{(2R)-6-[3-(4-methoxybenzyloxy)-2-methylpropyl]-5,6-dihydro-2H-pyran-2-yl}-ethanol 
• 856410-47-4 tert-butoxy-{4-[6-(4,4-dibromo-2-methyl-but-3-enyl)-5,6-dihydro-2H-pyran-2-yl]-but-2-ynyloxy}-diphenyl-silane 
• 13170-43-9 (trimethylsilyl)methylmagnesium chloride 

Downstream Products

• 856410-72-5 4-{(2R,6R)-6-[(7E,12E)-(2S,6S,10S,11S)-6,11-Bis-(tert-butyl-dimethyl-silanyloxy)-10-(4-methoxy-benzyloxy)-2-methyl-13-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-4-methylene-trideca-7,12-dienyl]-5,6-dihydro-2H-pyran-2-yl}-but-2-yn-1-ol 
• 856410-69-0 2-(3-{6-[4-(tert-butoxy-diphenyl-silanyloxy)-but-2-ynyl]-3,6-dihydro-2H-pyran-2-yl}-2-methyl-propyl)-9-(tert-butyl-dimethyl-silanyloxy)-8-(4-methoxy-benzyloxy)-11-(4-methyl-3,6-dihydro-2H-pyran-2-yl)-undeca-1,5,10-trien-4-ol 
• 856410-70-3 2-(3-{6-[4-(tert-butoxy-diphenyl-silanyloxy)-but-2-ynyl]-3,6-dihydro-2H-pyran-2-yl}-2-methyl-propyl)-9-(tert-butyl-dimethyl-silanyloxy)-8-(4-methoxy-benzyloxy)-11-(4-methyl-3,6-dihydro-2H-pyran-2-yl)-undeca-1,5,10-trien-4-one 
• 856410-48-5 2-(3-{6-[4-(tert-butoxy-diphenyl-silanyloxy)-but-2-ynyl]-3,6-dihydro-2H-pyran-2-yl}-2-methyl-propyl)-9-(tert-butyl-dimethyl-silanyloxy)-8-(4-methoxy-benzyloxy)-11-(4-methyl-3,6-dihydro-2H-pyran-2-yl)-undeca-1,5,10-trien-4-ol 
• 856410-71-4 C₆₆H₉₈O₈Si₃ 
• 115268-43-4 laulimalide 
• 856410-36-1 6-[4-(tert-butoxy-diphenyl-silanyloxy)-but-2-ynyl]-2-(2-methyl-4-trimethylsilanylmethyl-pent-4-enyl)-3,6-dihydro-2H-pyran 

Relevant academic research and scientific papers

Total synthesis of (-)-laulimalide: Pd-catalyzed stereospecific ring construction of the substituted 3,6-dihydro[2H]pyran units

(Chemical Equation Presented) The potent anticancer agent (-)-laulimalide (1) was prepared through a versatile method that should allow access to other marine natural products. Key steps included a Pd-catalyzed 1,3 chirality transfer of an allylic alcohol