85646-99-7

Upstream product

• 85646-98-6 2-benzyl-1,2,3,4-tetrahydro-9H-pyrido<3,4-b>indole-1-propionitrile 
• 15741-79-4 N-benzyl tryptamine 
• 75304-05-1 2-benzyl-1,2,3,4-tetrahydro-9H.pyrido<3,4-b>indole-1-propionic acid 
• 85580-15-0 methyl 2-benzyl-1,2,3,4-tetrahydro-9H-pyrido<3,4-b>indole-1-propionate 
• 84094-78-0 3-((R)-2-Benzyl-2,3,4,9-tetrahydro-1H-β-carbolin-1-yl)-propionitrile 
• 63229-68-5 methyl N-benzyl-L-tryptophanate 
• 84094-80-4 (1R,3S)-2-Benzyl-1-(2-cyano-ethyl)-2,3,4,9-tetrahydro-1H-β-carboline-3-carbonitrile 
• 84094-76-8 (1R,3S)-2-Benzyl-1-(2-carbamoyl-ethyl)-2,3,4,9-tetrahydro-1H-β-carboline-3-carboxylic acid amide 
• 60702-97-8 (1S,3S)-2-Benzyl-1-(2-carboxy-ethyl)-2,3,4,9-tetrahydro-1H-β-carboline-3-carboxylic acid methyl ester 
• 135558-10-0 (1S,3S)-2-Benzyl-1-(2-methoxycarbonyl-ethyl)-2,3,4,9-tetrahydro-1H-β-carboline-3-carboxylic acid methyl ester 

Relevant academic research and scientific papers

ASYMMETRIC SYNTHESIS OF (1S)-(-)-TRYPARGINE

(1S)-(-)-Trypargine 8(1a) was synthesized from (1S,3R)-(-)-2-benzyl-3-(methoxycarbonyl)-1,2,3,4-tetrahydro-9H-pyridoindole-1-propionic acid (3a), prepared by the asymmetric Pictet-Spengler reaction of Nb-benzyl-(D)-tryptophan methyl este

A New Synthesisof(+/-)Trypargine

A new route for the synthesis of (+/-)-trypargine (I) is described.The Pictet-Spengler reaction of Nb-benzyltryptamine with α-ketoglutaric acid was carried out in aprotic media to afford the key intermediate, 2-benzyl-1,2,3,3-tetrahydro-9H-pyri