85653-33-4Relevant academic research and scientific papers
Sodium in liquid ammonia - A versatile tool in modifications of arylphosphine oxides
Stankevi?, Marek,W?odarczyk, Adam,Jaklińska, Magdalena,Parcheta, Renata,Pietrusiewicz, K. Micha?
experimental part, p. 8671 - 8678 (2011/12/03)
A simple and practical method for modifications of tertiary arylphosphine oxides based on their reaction with sodium in liquid ammonia is presented. Depending on the structure of the starting compounds, either dearomatisation of the phenyl substituent or cleavage of a P-aryl bond from phosphorus atom can be selectively performed and the corresponding (1,4-cyclohexadien-3-yl)phosphine oxides or secondary phosphine oxides were obtained in good to excellent yields.
Lewis acid catalyzed room-temperature Michaelis-Arbuzov rearrangement
Renard, Pierre-Yves,Vayron, Philippe,Leclerc, Eric,Valleix, Alain,Mioskowski, Charles
, p. 2389 - 2392 (2007/10/03)
The taming of the shrew! For the first time, a broadly applicable efficient room-temperature Arbuzov rearrangement is described. This reaction is accomplished through an atom-economical Lewis acid catalyzed process (see scheme, TMSOTf=trimethylsilyl trifluoromethane-sulfonate). The method has been generalized to primary and activated secondary phosphites, phosphinites, and phosphonites.
