856562-88-4

Usage

Uses

Used in Organic Synthesis:
(R)-1-O-TOLYLETHANAMINE-HCl is used as a chiral building block for the synthesis of various biologically active molecules. Its unique structure allows for the creation of compounds with specific stereochemistry, which is crucial for biological activity and selectivity.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (R)-1-O-TOLYLETHANAMINE-HCl serves as a valuable precursor in the development of new drugs. Its chiral nature enables the production of enantiomerically pure compounds, which can have different pharmacological effects and reduce potential side effects.
Used in Agrochemical Production:
(R)-1-O-TOLYLETHANAMINE-HCl is also utilized as a precursor in the production of agrochemicals, where its chiral properties can contribute to the development of more effective and selective pesticides or other agricultural products.
Used in Drug Development and Pharmacological Studies:
(R)-1-O-TOLYLETHANAMINE-HCl plays a role in the study of drug interactions and pharmacological mechanisms. Its use in research helps to understand the behavior of different drug candidates and their interactions with biological targets, ultimately contributing to the advancement of drug discovery and development.

Upstream product

• 577-16-2 2-Methylacetophenone 
• 35106-87-7 1-o-tolylethanamine hydrochloride 
• 42142-17-6 1-(o-tolyl)ethanamine 
• 194024-39-0 N-benzyl-1-(o-tolyl)ethan-1-amine 
• 1307727-86-1 1-phenyl-N-(1-(o-tolyl)ethylidene)methanamine 

Relevant academic research and scientific papers

Sequential reductive amination-hydrogenolysis: A one-pot synthesis of challenging chiral primary amines

Difficult-to-access chiral primary amines were formed in good to high yield and ee using a rare example of a one-pot synthesis from prochiral ketones (sequential reductive amination-hydrogenloysis). As a highlight we also demonstrate a one-pot reductive amination-hydrogenolysis-reductive amination (five reactions) of ortho-methoxyacetophenone resulting in the chiral diamine 1-(2-methoxyphenyl)ethyl-(2-pyridylmethyl)-amine (4) (58% overall yield, >99% ee), a new organocatalyst for aqueous enantioselective aldol reactions. Copyright

NOVEL URACIL COMPOUND HAVING INHIBITORY ACTIVITY ON HUMAN DEOXYURIDINE TRIPHOSPHATASE OR SALT THEREOF

Provided is a uracil compound or a salt thereof, which has potent human dUTPase inhibitory activity and is useful as, for example, an antitumor drug. A uracil compound represented by the general formula (I) or a salt thereof: wherein n represents an integer of 1 to 3; X represents a bond, an oxygen atom, a sulfur atom, or the like; Y represents a linear or branched alkylene group having 1 to 8 carbon atoms, or the like; and Z represents -SO2NR1R2 or -NR3SO2-R4, wherein R1 and R2 each represent an alkyl group having 1 to 6 carbon atoms, an aralkyl group which is optionally substituted, or the like; R3 represents an alkyl group having 1 to 6 carbon atoms, or the like; and R4 represents an aromatic hydrocarbon group, an unsaturated heterocyclic group, or the like.