856568-04-2

Basic information

• Product Name: 5-Thiazolamine, 2,4-dimethyl-
• Synonyms: 5-Thiazolamine, 2,4-dimethyl-;5-AMino-2,4-diMethylthiazole;2,4-dimethylthiazol-5-amine
• CAS NO: 856568-04-2
• Molecular Formula: C₅H₈N₂S
• Molecular Weight: 128.2
• Product Categories: Aromatics, Miscellaneous Reagents, Sulfur & Selenium Compounds
• Mol File: 856568-04-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-Thiazolamine, 2,4-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Thiazolamine, 2,4-dimethyl-(856568-04-2)
• EPA Substance Registry System: 5-Thiazolamine, 2,4-dimethyl-(856568-04-2)

Safety Data

• Hazardous Substances Data: 856568-04-2(Hazardous Substances Data)

Usage

Uses

5-Amino-2,4-dimethylthiazole is used in the preparation of [2,1-f][1,2,4]triazin-4(3H)-one compounds as CRF antagonists.

Upstream product

• 412307-72-3 N-(2,4-dimethyl-thiazol-5-yl)-acetamide 
• 860182-77-0 (2,4-dimethyl-thiazol-5-yl)-carbamic acid ethyl ester 
• 541-58-2 2,4-dimethylthiazole 
• 20751-81-9 2,4-Dimethyl-5-nitro-thiazol 
• 7210-77-7 ethyl 2,4-dimethyl-1,3-thiazole-5-carboxylate 

Downstream Products

• 857623-15-5 N-acetyl-sulfanilic acid-(2,4-dimethyl-thiazol-5-ylamide) 

Relevant articles and documents

5-aminothiazole non-steroidal anti-inflammatory compound as well as preparation method and application thereof

The invention discloses a 5-aminothiazole non-steroidal anti-inflammatory compound. The compound which is efficient, low in toxicity and small in side effect is prepared from an ester intermediate containing a thiazine ring and a 5-aminothiazole derivative through a transesterification reaction. The preparation method of the compound is simple, the compound has the active groups of the existing non-steroidal anti-inflammatory medicine; meanwhile, the special change of the nitrogen atom position is also designed; compared with the existing non-steroidal anti-inflammatory medicines, the compoundhas better anti-inflammatory and analgesic effects, particularly has good curative effects on arthritis, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, soft tissue inflammation and thelike, has small toxic and side effects on human bodies, and has a very wide market prospect.