85661-17-2

Basic information

• Product Name: 6-[2-(2,4-dichlorophenoxy)ethoxy]-5,6,7,8-tetrahydropyrimido[4,5-d]pyrimidine-2,4-diamine
• CAS NO: 85661-17-2
• Molecular Formula: C₁₄H₁₆Cl₂N₆O₂
• Molecular Weight: 371.2218
• Mol File: 85661-17-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 655.4°C at 760 mmHg
• Flash Point: 350.2°C
• Density: 1.56g/cm³
• Vapor Pressure: 4.71E-17mmHg at 25°C
• Refractive Index: 1.698
• CAS DataBase Reference: 6-[2-(2,4-dichlorophenoxy)ethoxy]-5,6,7,8-tetrahydropyrimido[4,5-d]pyrimidine-2,4-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-[2-(2,4-dichlorophenoxy)ethoxy]-5,6,7,8-tetrahydropyrimido[4,5-d]pyrimidine-2,4-diamine(85661-17-2)
• EPA Substance Registry System: 6-[2-(2,4-dichlorophenoxy)ethoxy]-5,6,7,8-tetrahydropyrimido[4,5-d]pyrimidine-2,4-diamine(85661-17-2)

Safety Data

• Hazardous Substances Data: 85661-17-2(Hazardous Substances Data)

Upstream product

• 1004-38-2 2,4,6-triaminopyrimidine 
• 50-00-0 formaldehyd 
• 15269-72-4 O-[2-(2,4-Dichloro-phenoxy)-ethyl]-hydroxylamine; hydrochloride 

Relevant articles and documents

An Application of the Mannich Reaction Using Hydroxylamine and Some of its Derivatives. 6-Substituted-2,4-diamino-5,6,7,8-tetrahydropyrimidopyrimidines

Hydroxylamine and some of its O-substituted derivatives (2) have been used as the amine component in Mannich reactions with 2,4,6-triaminopyrimidine (1).The resulting 6-substituted tetrahydropyrimidopyrimidines (3) contain an N-O bond linking the substituent to the ring.These results extend the utility of this modified Mannich reaction to otherwise inaccessible substituents.Reaction conditions, spectral data and certain limitations of the reaction are discussed.