856629-10-2Relevant academic research and scientific papers
COVALENT RAS INHIBITORS AND USES THEREOF
-
Page/Page column 187, (2021/06/04)
The disclosure features compounds, or pharmaceutically acceptable salts thereof, alone and in combination with other therapeutic agents, pharmaceutical compositions, and protein conjugates thereof, capable of modulating biological processes including Ras, and their uses in the treatment of cancers.
Nucleophilic ring-opening of activated aziridines: A one-step method for labeling biomolecules with fluorine-18
Roehn, Ulrike,Becaud, Jessica,Mu, Linjing,Srinivasan, Ananth,Stellfeld, Timo,Fitzner, Ansgar,Graham, Keith,Dinkelborg, Ludger,Schubiger, August P.,Ametamey, Simon M.
scheme or table, p. 902 - 912 (2009/12/31)
The direct labeling of biomolecules with fluorine-18 is highly desirable. An option is the ring-opening of an activated aziridine moiety in a biomolecule using 18F-fluoride. Therefore, a series of aziridine-based model compounds and three aziri
Radiolabelling via fluorination of aziridines
-
, (2008/12/06)
This invention relates to novel compounds comprising arziridine ring suitable for labelling or already labelled with an appropriate halogen, preferably 18F, methods of preparing such compounds, compositions comprising such compounds, kits comprising such compounds or compositions and uses of such compounds, compositions or kits for diagnostic imaging, preferably positron emission tomography (PET).
