856629-37-3

Usage

Uses

Used in Pharmaceutical Research:
1-(2-Chlorophenyl)ethanamine hydrochloride is used as a research chemical for studying the effects and mechanisms of action of psychoactive substances, particularly those affecting neurotransmitter release and the central nervous system.
Used in Neuroscientific Research:
In the field of neuroscience, 1-(2-Chlorophenyl)ethanamine hydrochloride serves as a tool to investigate the role of neurotransmitters in various brain functions and disorders, contributing to a better understanding of neurochemical processes.
Used in Toxicological Studies:
Due to its potential neurotoxicity, 1-(2-Chlorophenyl)ethanamine hydrochloride is utilized in toxicological research to explore the effects of high doses on the brain and to develop potential countermeasures or treatments for overdose situations.
Used in Forensic Analysis:
In forensic science, 1-(2-Chlorophenyl)ethanamine hydrochloride may be analyzed in biological samples to detect its presence in cases of substance abuse or poisoning, aiding in the investigation of related crimes or incidents.

Upstream product

• 1164111-49-2 C₈H₈ClN*ClH 
• 2142-68-9 1-(2-chlorophenyl)ethanone 
• 873-31-4 2-chlorophenylacetylene 

Relevant academic research and scientific papers

Synthesis method of primary amine hydrochloride

The invention discloses a synthesis method of primary amine hydrochloride. According to the synthesis method, in the presence of a gold complex, water and alkyne carry out catalytic hydrolysis to generate ketones, and then ketones and ammonium formate are catalyzed by a rhodium complex to generate primary amine. Compared with a conventional primary amine synthesis method, the synthesis method hasthe advantages that no alkali is added during the reaction process, no side product is generated, the atomic economy is good, the reaction conditions are mild, and the synthesis method has a wide prospect.

NOVEL URACIL COMPOUND HAVING INHIBITORY ACTIVITY ON HUMAN DEOXYURIDINE TRIPHOSPHATASE OR SALT THEREOF

Provided is a uracil compound or a salt thereof, which has potent human dUTPase inhibitory activity and is useful as, for example, an antitumor drug. A uracil compound represented by the general formula (I) or a salt thereof: wherein n represents an integer of 1 to 3; X represents a bond, an oxygen atom, a sulfur atom, or the like; Y represents a linear or branched alkylene group having 1 to 8 carbon atoms, or the like; and Z represents -SO2NR1R2 or -NR3SO2-R4, wherein R1 and R2 each represent an alkyl group having 1 to 6 carbon atoms, an aralkyl group which is optionally substituted, or the like; R3 represents an alkyl group having 1 to 6 carbon atoms, or the like; and R4 represents an aromatic hydrocarbon group, an unsaturated heterocyclic group, or the like.

Enantioselective hydrogenation of N-H imines

(Figure Presented) N-H ketoimines 3a-3v are readily prepared in high yield via organometallic addition to nitriles and isolated as corresponding bench-stable hydrochloride salts. Homogeneous asymmetric hydrogenation of unprotected N-H ketoimines 3a-3v usi