856659-47-7Relevant academic research and scientific papers
New application of Pictet-Spengler reaction leading to the synthesis of an unusual seven-membered heterocyclic ring system
Kundu, Bijoy,Sawant, Devesh,Partani, Pankaj,Kesarwani, Amit P.
, p. 4889 - 4892 (2007/10/03)
A novel strategy for the Pictet-Spengler reaction is reported. Our strategy involves reaction of arylamines, linked to the N-1 of disubstituted imidazoles, with aldehydes in the presence of p-TsOH. The iminium ion generated in situ undergoes C-C bond form
