856702-64-2Relevant academic research and scientific papers
General suzuki coupling of heteroaryl bromides by using tri-tert-butylphosphine as a supporting ligand
Zou, Yinjun,Yue, Guizhou,Xu, Jianwei,Zhou, Jianrong
, p. 5901 - 5905 (2014)
A general procedure for the fast Suzuki coupling of major families of heteroaryl bromides was realized by using Pd(OAc)2/PtBu3 as the catalyst. Many couplings were finished within minutes at room temperature in n-butanol. Different from previous studies, three typical heteroaryl bromides were systematically examined in couplings of various heteroaryl and aryl boronic acids. A fast, general coupling of heteroaryl bromides is realized by using a single palladium catalyst supported by tri-tert-butylphosphine.
