856765-85-0

Upstream product

• 1125-88-8 benzaldehyde dimethyl acetal 
• 121998-84-3 (2R,3R,4E)-octadec-4-ene-1,2,3-triol 

Downstream Products

• 856765-86-1 (4R,5S)-5-azido-4-((E)-pentadec-1-en-1-yl)-2-phenyl-1,3-dioxane 
• 103348-49-8 2-azido-sphingosine 
• 123-78-4 (2S,3R,4E)-2-amino-4-octadecene-1,3-diol 

Relevant academic research and scientific papers

Stereoselective Synthesis of D(+)-erythro and L(-)-threo Sphingosines from Carbohydrates

Stereocontrolled syntheses of D(+)-erythro and L(-)-threo shingosines are described starting from D-xylose and D-arabinose respectively through acetylenic intermediates 3 and 4, obtained by base induced double elimination of the β-alkoxy chlorides 5 and 13. Keywords: D(+)-erythro and L(-)-threo sphingosines; base induced double elimination reaction; acetylenic alcohol

Horner-Wittig Reaction of Dimethyl 2,3-O-Isopropylidene-D-glyceroylmethylphosphonate and Its Application to the Formal Synthesis of D-erythro-C18-Sphingosine

Dimethyl 1,2-O-isopropylidene-D-glyceroylmethylphosphonate was found to react with aldehyde in the presence of cesium carbonate in isopropyl alcohol.Using this reaction the formal synthesis of D-erythro-C18-sphingosine was achieved.