85683-73-4Relevant academic research and scientific papers
Formation of benzynes from 2,6-dihaloaryllithiums: Mechanistic basis of the regioselectivity
Ramirez, Antonio,Candler, John,Bashore, Crystal G.,Wirtz, Michael C.,Coe, Jotham W.,Collum, David B.
, p. 14700 - 14701 (2004)
The key elimination step for the formation of 3-chloro- and 3-fluorobenzyne from 2-chloro-6-fluorophenyllithium displays a pronounced solvent-dependent regioselectivity. 6Li and 13C NMR spectroscopic studies on 2-chloro-6-fluorophenyllithium reveal a single monomeric aryllithium, suggested by DFT computational studies to be a trisolvate. Rate studies indicate that the elimination of LiCl and LiF proceeds via trisolvated and disolvated monomers, respectively. Copyright
Structural and rate studies of the formation of substituted benzynes
Riggs, Jason C.,Ramirez, Antonio,Cremeens, Matthew E.,Bashore, Crystal G.,Candler, John,Wirtz, Michael C.,Coe, Jotham W.,Collum, David B.
, p. 3406 - 3412 (2008/09/20)
The key elimination step for the formation of 3-substituted and 3,6-disubstituted benzynes from 2-haloaryllithiums displays a pronounced solvent-dependent regioselectivity. All 2-haloaryllithiums with electron withdrawing groups in the 6 position are show
