856842-30-3Relevant academic research and scientific papers
Selection of a respiratory syncytial virus fusion inhibitor clinical candidate, part 1: Improving the pharmacokinetic profile using the structure-property relationship
Bonfanti, Jean-Fran?ois,Doublet, Frédéric,Fortin, Jér?me,Lacrampe, Jean,Guillemont, Jér?me,Muller, Philippe,Queguiner, Laurence,Arnoult, Eric,Gevers, Tom,Janssens, Peggy,Szel, Heidi,Willebrords, Rudy,Timmerman, Philip,Wuyts, Koen,Janssens, Frans,Sommen, Cois,Wigerinck, Piet,Andries, Koen
, p. 4572 - 4584 (2007)
We previously reported the discovery of substituted benzimidazole fusion inhibitors with nanomolar activity against respiratory syncytial virus (Andries, K.; et al. Antiviral Res. 2003, 60, 209-219). A lead compound of the series was selected for preclini
AMINO-BENZIMIDAZOLES DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION
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Page/Page column 23, (2008/06/13)
The present invention concerns amino-benzimidazoles having inhibitory activity on the replication of the respiratory syncytial virus and having the formula (I) their prodrugs, N-oxides, addition salts, quaternary amines, metal complexes and stereochemical
