856865-43-5

Basic information

• Product Name: (R)-1-(4-bromophenyl)hexan-1-ol
• Synonyms: (R)-1-(4-bromophenyl)hexan-1-ol
• CAS NO: 856865-43-5
• Molecular Weight: 257.17
• Mol File: 856865-43-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-1-(4-bromophenyl)hexan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-(4-bromophenyl)hexan-1-ol(856865-43-5)
• EPA Substance Registry System: (R)-1-(4-bromophenyl)hexan-1-ol(856865-43-5)

Safety Data

• Hazardous Substances Data: 856865-43-5(Hazardous Substances Data)

Upstream product

• 928-95-0 (E)-2-Hexen-1-ol 
• 821-41-0 5-Hexen-1-ol 
• 544-12-7 3-hexen-1-ol 
• 5467-74-3 4-Bromophenylboronic acid 
• 66-25-1 hexanal 
• 6725-74-2 1-bromo-4-(cyclopent-1-en-1-yl)benzene 
• 1357255-87-8 (2RS,6R)-2-hydroxy-6-(4-bromophenyl)tetrahydropyran 
• 1357255-86-7 5-(4-bromophenyl)-5-oxopentanal 
• 1357256-06-4 C₁₂H₁₅BrO 

Relevant articles and documents

Multicatalytic approach to one-pot stereoselective synthesis of secondary benzylic alcohols

One-pot procedures bear the potential to rapidly build up molecular complexity without isolation and purification of consecutive intermediates. Here, we report multicatalytic protocols that convert alkenes, unsaturated aliphatic alcohols, and aryl boronic acids into secondary benzylic alcohols with high stereoselectivities (typically >95:5 er) under sequential catalysis that integrates alkene cross-metathesis, isomerization, and nucleophilic addition. Prochiral allylic alcohols can be converted to any stereoisomer of the product with high stereoselectivity (>98:2 er, >20:1 dr).

EP2 RECEPTOR AGONISTS

A compound selected from Formula (iv) or Formula (iii); (iv) (1R,2S)-2[4-1(S)-hydroxyhexyl)phenyl]-5-oxo-cyclopentaneheptanoic acid [RSS] or (iii) (1R,2S)-2[4-1(R)-hydroxyhexyl)phenyl]-5-oxo-cyclopentaneheptanoic acid [RSR] or a salt, solvate, chemically protected form or prodrug thereof, and its use in treating conditions alleviated by agonism of an EP2 receptor.