856867-56-6

Basic information

• Product Name: Tedizolid phosphate impurity
• Synonyms: (R)-(3-(3-fluoro-4-(6-(1-methyl-1H-tetrazol-5-yl)pyridin-3-yl) phenyl)-2-oxooxazolidin-5-yl)methyl dihydrogen phosphate;Tedizolidted Impurity 5
• CAS NO: 856867-56-6
• Molecular Formula: C17H16FN6O6P
• Molecular Weight: 450.32
• Mol File: 856867-56-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 725.6±70.0 °C(Predicted)
• Appearance: /
• Density: 1.75±0.1 g/cm3(Predicted)
• PKA: 1.81±0.10(Predicted)
• CAS DataBase Reference: Tedizolid phosphate impurity(CAS DataBase Reference)
• NIST Chemistry Reference: Tedizolid phosphate impurity(856867-56-6)
• EPA Substance Registry System: Tedizolid phosphate impurity(856867-56-6)

Safety Data

• Hazardous Substances Data: 856867-56-6(Hazardous Substances Data)

Relevant articles and documents

NOVEL OXAZOLIDINONE DERIVATIVES

The present invention relates to novel derivatives of oxazolidinone, a method thereof and pharmaceutical compositions comprising the derivatives for use in an antibiotic. The oxazolidinone derivatives of the present invention show inhibitory activity against a broad spectrum of bacteria and lower toxicity. The prodrugs, prepared by reacting the compound having hydroxyl group with amino acid or phosphate, have an excellent efficiency on solubility thereof against water. Further, the derivatives of the present invention may exert potent antibacterial activity versus various human and animal pathogens, including Gram-positive bacteria such as Staphylococi, Enterococci and Streptococi, anaerobic microorganisms such as Bacteroides and Clostridia, and acid-resistant microorganisms such as Mycobacterium tuberculosis and Mycobacterium avium. Accordingly, the compositions comprising the oxazolidinone are used in an antibiotic.