857090-93-8Relevant academic research and scientific papers
Palladium-Catalyzed C12-Selective Direct Arylation of [1,2- c ]Quinazolin-6(5 H)-ones
Arcadi, Antonio,Cacchi, Sandro,Fabrizi, Giancarlo,Fochetti, Andrea,Ghirga, Francesca,Goggiamani, Antonella,Iazzetti, Antonia,Marinelli, Fabio
, p. 3287 - 3294 (2019)
A straightforward approach to the synthesis of the challenging 12-arylindolo[1,2- c ]quinazolin-6(5 H)-ones through the palladium-catalyzed direct arylation of N -benzyl and NH-free [1,2- c ]quinazolin-6(5 H)-ones with aryl halides is described.
One-pot synthesis of pyrimido[1,6-a ]indol-1(2 H)-one derivatives by a nucleophilic addition/Cu-catalyzed N-arylation/Pd-catalyzed C-H activation sequential process
Wang, Zhi-Jing,Yang, Jian-Guo,Yang, Fan,Bao, Weiliang
supporting information; experimental part, p. 3034 - 3037 (2010/09/05)
A novel and convenient one-pot synthesis of pyrimido[1,6-a]indol-1(2H)-one derivatives through a nucleophilic addition/Cu-catalyzed N-arylation/Pd- catalyzed C-H activation sequential process is described. The reaction of easily prepared ortho-gem-dibromovinyl isocyanates with N-alkyl-anilines gave the desired indole derivatives in moderate to good yields.
An iodoacetamide-based free radical cyclisation approach to the 7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one (paullone) system
Bremner, John B.,Sengpracha, Waya
, p. 5489 - 5498 (2007/10/03)
A potentially versatile route to 2-(2-aminoaryl)indoles is described based on a palladium-mediated cyclisation of N-substituted indoles, together with free radical cyclisation of their N-benzyliodoacetamide derivatives to the 7,12-dihydro-indolo[3,2-d][1]
