Gefitinib-d8 is a deuterated analog of Gefitinib, an anti-cancer drug that belongs to the class of epidermal growth factor receptor inhibitors. It is characterized by the presence of eight deuterium atoms, which makes it a useful internal standard for the quantification of Gefitinib by GCor LC-mass spectrometry.
857091-32-8
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Basic information
- Product Name: Gefitinib D8
- Synonyms: Gefitinib D8
- CAS NO:857091-32-8
- Molecular Formula: C22H16ClD8FN4O3
- Molecular Weight: 454.951657424
- EINECS: N/A
- Product Categories: N/A
- Mol File: 857091-32-8.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: Gefitinib D8(CAS DataBase Reference)
- NIST Chemistry Reference: Gefitinib D8(857091-32-8)
- EPA Substance Registry System: Gefitinib D8(857091-32-8)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 857091-32-8(Hazardous Substances Data)
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857091-32-8 Usage
Uses
Used in Pharmaceutical Industry:Gefitinib-d8 is used as an internal standard for the quantification of Gefitinib by GCor LC-mass spectrometry. This application is crucial for ensuring accurate and precise measurements of Gefitinib levels in various samples, such as biological fluids or pharmaceutical formulations.
Used in Cancer Research and Treatment:
Gefitinib-d8 is used as a research tool to study the mechanism of action and efficacy of Gefitinib in targeting and blocking signaling pathways implicated in the growth and survival of cancer cells. This helps researchers to better understand the drug's potential and limitations in treating various types of cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 857091-32-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,7,0,9 and 1 respectively; the second part has 2 digits, 3 and 2 respectively.Calculate Digit Verification of CAS Registry Number 857091-32:
(8*8)+(7*5)+(6*7)+(5*0)+(4*9)+(3*1)+(2*3)+(1*2)=188
188 % 10 = 8
So 857091-32-8 is a valid CAS Registry Number.
857091-32-8Upstream product
857091-32-8Downstream Products
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Gefitinib D8
