85714-55-2Relevant academic research and scientific papers
Nucleosides. 133. Synthesis of 5-alkenyl-1-(2-deoxy-2-fluoro- β-D-arabinofuranosyl)cytosines and related pyrimidine nucleosides as potential antiviral agents
Perlman,Watanabe,Schinazi,Fox
, p. 741 - 748 (2007/10/02)
The synthesis of 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)cytosines with a halovinyl (8 and 9) or vinyl (10) substituent at C-5 was accomplished from the corresponding 5-iodo (FIAC, 1) and/or 5-chloromercuri (5) nucleoside analogues with use of Li2/
Acetylenic Nucleosides. 3. Synthesis and Biological Activities of Some 5-Ethynylpyrimidine Nucleosides
Sharma, Ram A.,Kavai, Ivan,Hughes, Robert G.,Bobek, Miroslav
, p. 410 - 412 (2007/10/02)
Iodination of 1-(2,3,5-tri-O-acetyl-β-D-arabinofuranosyl)uracil furnished the 5-iodo derivative (Ib), which on treatment with (trimethylsilyl)acetylene in the presence of catalytic amounts of (Ph3P)2PdCl2/CuI and subsequent deblocking, afforded 1-β-D-arab
5-Substituted 1-(2'-Deoxy-2'-substituted-β-D-arabinofuranosyl)pyrimidine nucleosides
-
, (2008/06/13)
Pyrimidine nucleosides exhibiting anti-viral and anti-tumor effects have the formula STR1 wherein A is OR3, SR3, NR3 R4 or NHacyl wherein R3 and R4 are the same or different and are hydroge
