85714-55-2

Basic information

• Product Name: 4-amino-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-ethynylpyrimidin-2(1H)-one
• CAS NO: 85714-55-2
• Molecular Formula: C₁₁H₁₂FN₃O₄
• Molecular Weight: 269.2291
• Mol File: 85714-55-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 478.5°C at 760 mmHg
• Flash Point: 243.2°C
• Density: 1.62g/cm³
• Vapor Pressure: 3.64E-11mmHg at 25°C
• Refractive Index: 1.655
• CAS DataBase Reference: 4-amino-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-ethynylpyrimidin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-amino-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-ethynylpyrimidin-2(1H)-one(85714-55-2)
• EPA Substance Registry System: 4-amino-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-ethynylpyrimidin-2(1H)-one(85714-55-2)

Safety Data

• Hazardous Substances Data: 85714-55-2(Hazardous Substances Data)

Upstream product

• 56632-81-6 1,3-di-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranosyl bromide 
• 69123-90-6 fiacitabine 
• 95740-22-0 1-((2R,3S,4R,5R)-3-Fluoro-4-trimethylsilanyloxy-5-trimethylsilanyloxymethyl-tetrahydro-furan-2-yl)-4-imino-5-trimethylsilanylethynyl-3,4-dihydro-1H-pyrimidin-2-one 
• 95740-24-2 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-<2-(trimethylsilyl)ethynyl>cytosine 

Relevant articles and documents

Nucleosides. 133. Synthesis of 5-alkenyl-1-(2-deoxy-2-fluoro- β-D-arabinofuranosyl)cytosines and related pyrimidine nucleosides as potential antiviral agents

The synthesis of 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)cytosines with a halovinyl (8 and 9) or vinyl (10) substituent at C-5 was accomplished from the corresponding 5-iodo (FIAC, 1) and/or 5-chloromercuri (5) nucleoside analogues with use of Li2/

5-Substituted 1-(2'-Deoxy-2'-substituted-β-D-arabinofuranosyl)pyrimidine nucleosides

Pyrimidine nucleosides exhibiting anti-viral and anti-tumor effects have the formula STR1 wherein A is OR3, SR3, NR3 R4 or NHacyl wherein R3 and R4 are the same or different and are hydroge