857252-39-2

Upstream product

• 857252-38-1 N,N-diethyl-4-{6-methoxy-2-[(4-nitrophenyl)sulfonyl]-1,2,3,4-tetrahydroisoquinolin-1-yl}benzamide 

Downstream Products

• 857252-41-6 1-{4-[(diethylamino)carbonyl]phenyl}-2-[(4-nitrophenyl)sulfonyl]-1,2,3,4-tetrahydroisoquinolin-6-yl dimethylsulfamate 
• 857252-40-5 1-{4-[(diethylamino)carbonyl]phenyl}-2-[(4-nitrophenyl)sulfonyl]-1,2,3,4-tetrahydroisoquinolin-6-yl methanesulfonate 

Relevant academic research and scientific papers

1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVES, PREPARATIONS THEREOF AND USES THEREOF

Compounds of general formula (I) wherein D, E, R1, R2, R3, R4, R5, R6 and R7 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.