857261-39-3

Upstream product

• 51352-18-2 methyl 2-(3-methoxy-5-methylphenyl)acetate 
• 857261-38-2 [3-(tert-butyl-dimethyl-silanyloxy)-5-trifluoromethanesulfonyloxy-phenyl]-acetic acid methyl ester 
• 594-27-4 tetramethylstannane 

Downstream Products

• 857261-40-6 (3-dimethylthiocarbamoyloxy-5-methyl-phenyl)-acetic acid methyl ester 

Relevant academic research and scientific papers

Non-nucleoside reverse transcriptase inhibitors

The present invention provides compounds for treating or preventing an HIV infection, or treating AIDS or ARC comprising administering a compound according to formula I where Ar, R1-R5, R7a, R7b, R7c, R8-R10, X1, X2 m, n, o and p are as defined herein.

(5- (2-PHENYL)-THIAZOL-5-YLMETHOXY)-INDOL-1-YL) -ACETIC ACID DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF THE HUMAN PPAR-DELTA RECEPTOR FOR THE TREATMENT OF METABOLIC DISORDERS SUCH AS TYPE 2 DIABETES

Disclosed are compounds having the structure of Formula (I) and pharmaceutically acceptable salts and solvates thereof [A]-[B]-[C] (I) wherein (a) [A] is [H]-[L]; wherein [H] represents a CCOH (or a hydrolyzable ester thereof) or tetrazole group [L] is: formula (II), b) [B] is a ring system selected from the group consisting of: e.g. formula (III); (IIIA), c) [C] is e.g. formula (IV); the other substituents and variables are defined in the claims; as modulators of the human PPAR-delta receptor for the treatment of metabolic disorders such as type 2 diabetes.