Cas 857264-44-9,N-(2-{[(2S)-2-amino-3-(5-fluoro-1'H,3H-spiro[1-benzofuran-2,4'-piperidin]-1'-yl)propyl]oxy}-4-methoxyphenyl)acetamide

857264-44-9

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Basic information

Product Name: N-(2-{[(2S)-2-amino-3-(5-fluoro-1'H,3H-spiro[1-benzofuran-2,4'-piperidin]-1'-yl)propyl]oxy}-4-methoxyphenyl)acetamide
Synonyms: N-(2-{[(2S)-2-amino-3-(5-fluoro-1'H,3H-spiro[1-benzofuran-2,4'-piperidin]-1'-yl)propyl]oxy}-4-methoxyphenyl)acetamide
CAS NO:857264-44-9
Molecular Formula:
Molecular Weight: 443.518
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: N-(2-{[(2S)-2-amino-3-(5-fluoro-1'H,3H-spiro[1-benzofuran-2,4'-piperidin]-1'-yl)propyl]oxy}-4-methoxyphenyl)acetamide(CAS DataBase Reference)
NIST Chemistry Reference: N-(2-{[(2S)-2-amino-3-(5-fluoro-1'H,3H-spiro[1-benzofuran-2,4'-piperidin]-1'-yl)propyl]oxy}-4-methoxyphenyl)acetamide(857264-44-9)
EPA Substance Registry System: N-(2-{[(2S)-2-amino-3-(5-fluoro-1'H,3H-spiro[1-benzofuran-2,4'-piperidin]-1'-yl)propyl]oxy}-4-methoxyphenyl)acetamide(857264-44-9)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 857264-44-9(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 857264-44-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,7,2,6 and 4 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 857264-44:
(8*8)+(7*5)+(6*7)+(5*2)+(4*6)+(3*4)+(2*4)+(1*4)=199
199 % 10 = 9
So 857264-44-9 is a valid CAS Registry Number.

857264-44-9Upstream product

51779-32-9 iminodicarboxylic acid di-tert-butyl ester

857264-44-9Downstream Products

857264-44-9Relevant academic research and scientific papers

Spirocyclic compounds, potent CCR1 antagonists

Hossain, Nafizal,Ivanova, Svetlana,Bergare, Jonas,Eriksson, Tomas

, p. 1883 - 1886 (2013/04/10)

Conformationally constrained spirocycles (17-23) and (31-36) were synthesised. In vitro data revealed that these compounds are CCR1 antagonists with sub-nanomolar potency. In a functional assay 22, 23 and 36 inhibited CCR1 mediated chemotaxis with an ICs

NOVEL TRICYCLIC SPIRODERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

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Page/Page column 31-32, (2008/06/13)

The invention provides compounds of formula (I) wherein m, R1, n, R2, q, p, X, Y, R3, R4, t and, R5 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.

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