85729-23-3 Usage
Type of compound
Indole derivative (heterocyclic aromatic organic compound)
Industrial use
Pharmaceutical industry (precursor for drug synthesis)
Biological activities
Anti-inflammatory and antitumor properties (potential)
Utilization
Building block in organic synthesis (for producing other valuable compounds)
Role
Crucial in synthetic organic chemistry and medicinal chemistry (as a starting material for pharmaceutical products development)
Check Digit Verification of cas no
The CAS Registry Mumber 85729-23-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,7,2 and 9 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 85729-23:
(7*8)+(6*5)+(5*7)+(4*2)+(3*9)+(2*2)+(1*3)=163
163 % 10 = 3
So 85729-23-3 is a valid CAS Registry Number.
85729-23-3Relevant academic research and scientific papers
REACTION OF α-(3-INDOLYL)NITRONES WITH ARYL ISOCYANATES INCLUDING MIGRATION OF THE INDOLE RESIDUE
Velezheva, V. S.,Yaroslavskii, I. S.,Suvorov, N. N.
, p. 544 - 548 (2007/10/02)
When heated with aryl isocyanates, α-(3-indolyl)-N-aryl(alkyl)nitrones are converted into N-aryl-N'-aryl(alkyl)-N'-(3-indolyl)amidines.Subsequent hydrolysis of the N,N'-diphenyl-N'-(3-indolyl)amidine leads to 3-indolylformamide and 3-phenylaminoindole hydrochloride.When heated with acetic anhydride both with and without sodium acetate, the same nitrones are converted into the corresponding amides of 3-indolecarboxylic acid.The amide and ring nitrogen atoms are acylated simultaneously.N-Methyl-3-indolecarboxamide was obtained by the irradiation of α-(3-indolyl)-N-methylnitrone.
