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Spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one hydrochloride is a unique spiro compound characterized by the fusion of a piperidine ring and an oxazine ring, connected by a spiro carbon atom. As a hydrochloride salt, it features a positively charged piperidin-2-one group neutralized by a chloride ion. spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one hydrochloride holds promise in the pharmaceutical sector due to its distinctive molecular architecture and potential biological activities, making it a candidate for the development of novel therapeutic agents.

85732-37-2

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85732-37-2 Usage

Uses

Used in Pharmaceutical Industry:
Spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one hydrochloride serves as a key intermediate in the synthesis of various pharmaceutical agents. Its unique molecular structure allows for the exploration of its potential as a therapeutic agent, particularly in medicinal chemistry and drug development. spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one hydrochloride's ability to be modified and incorporated into new drug molecules makes it valuable for the treatment of a range of medical conditions.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one hydrochloride is utilized as a scaffold for the design and synthesis of new bioactive molecules. Its structural features facilitate the development of compounds with specific biological activities, targeting various disease pathways and offering potential therapeutic benefits.
Used in Drug Development:
Spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one hydrochloride plays a crucial role in drug development, where it is employed as a building block for the creation of innovative pharmaceuticals. Its unique properties and potential interactions with biological targets make it a promising candidate for the discovery of new drugs with improved efficacy and selectivity.

Check Digit Verification of cas no

The CAS Registry Mumber 85732-37-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,7,3 and 2 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 85732-37:
(7*8)+(6*5)+(5*7)+(4*3)+(3*2)+(2*3)+(1*7)=152
152 % 10 = 2
So 85732-37-2 is a valid CAS Registry Number.

85732-37-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one hydrochloride

1.2 Other means of identification

Product number -
Other names spiro[1H-3,1-benzoxazine-4,4'-piperidine]-2-one,hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:85732-37-2 SDS

85732-37-2Relevant academic research and scientific papers

Novel Compounds

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Page/Page column 61, (2012/04/18)

The present invention relates to the new compounds of general formula I wherein A, U, V, X, Y, R1, R2 and R3 are defined as stated hereinafter, the tautomers, the isomers thereof, the diastereomers, the enantiomers, the hydrates, the mixtures and the salts thereof as well as the hydrates of the salts, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, medicaments containing these compounds, their use and processes for preparing them.

CGRP ANTAGONISTS

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Page/Page column 29, (2011/08/02)

The present invention relates to novel CGRP antagonists of the general formula (I) in which U, V, X, Y, R1, R2, R3 are defined as described below, the tautomers, isomers, diastereomers, enantiomers, hydrates, mixtures and salts thereof, and the hydrates of the salts, particularly the physiologically compatible salts thereof having inorganic or organic acids or bases, pharmaceuticals comprising said compounds, the use thereof, and the method for the production thereof.

Spiropiperidines. I. Synthesis of 1'-substituted spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one derivatives and evaluation of their antihypertensive activity

Takai,Obase,Teranishi,Karasawa,Kubo,Shuto,Kasuya,Hashikami,Karashima,Shigenobu

, p. 1129 - 1139 (2007/10/02)

General synthetic methods for the preparation of 4-(2-aminophenyl)-4-hydroxypiperidine derivatives have been developed. The application use of these derivatives in the synthesis of 1'-substituted spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one derivati

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