857349-11-2

Basic information

• Product Name: 4-(4-bromophenyl)-4-pentyn-1-ol
• Synonyms: 4-(4-bromophenyl)-4-pentyn-1-ol
• CAS NO: 857349-11-2
• Molecular Weight: 239.112
• Mol File: 857349-11-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 4-(4-bromophenyl)-4-pentyn-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-bromophenyl)-4-pentyn-1-ol(857349-11-2)
• EPA Substance Registry System: 4-(4-bromophenyl)-4-pentyn-1-ol(857349-11-2)

Safety Data

• Hazardous Substances Data: 857349-11-2(Hazardous Substances Data)

Upstream product

• 5390-04-5 pent-1-yn-5-ol 
• 589-87-7 1,4-bromoiodobenzene 

Downstream Products

• 857349-13-4 6-(4-(5-hydroxy-1-pentynyl)phenyl)-5-hexyn-1-ol 
• 857349-12-3 5-(4-(4-hydroxy-1-butynyl)phenyl)-4-pentyn-1-ol 
• 857348-96-0 5-(4-(4-oxobutyl)phenyl)pentanal 
• 857348-97-1 6-(4-(5-oxopentyl)phenyl)hexan-1-ol 
• 857349-90-7 5-(4-(4-hydroxybutyl)phenyl)pentan-1-ol 
• 857349-16-7 6-(4-(5-hydroxypentyl)phenyl)hexan-1-ol 
• 1333171-14-4 (6S)-2-nitro-6-({5-[4'-(trifluoromethoxy)[1,1'-biphenyl]-4-yl]-4-pentynyl}oxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine 
• 1333171-15-5 (6S)-6-{[5-(4'-fluoro[1,1'-biphenyl]-4-yl)-4-pentynyl]oxy}-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine 
• 1333171-16-6 (6S)-2-nitro-6-({5-[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]-4-pentynyl}oxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine 
• 1333171-17-7 (6S)-2-nitro-6-[(5-{4-[6-trifluoromethyl-3-pyridinyl]phenyl}-4-pentynyl)oxy]-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine 
• 1333171-18-8 (6S)-6-({5-[4'-(difluoromethoxy)[1,1'-biphenyl]-4-yl]-4-pentynyl}oxy)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine 
• 1333171-45-1 1-bromo-4-(5-bromo-1-pentynyl)benzene 
• 1333171-46-2 (6S)-6-{[5-(4-bromophenyl)-4-pentynyl]oxy}-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine 
• 1366543-67-0 1-bromo-4-(hex-5-en-1-ynyl)benzene 

Relevant articles and documents

Tetrahydroxydiboron-Promoted Radical Addition of Alkynols

Tetrahydroxydiboron has previously been used as a borylation or reducing reagent in organic synthesis. Herein, we present a novel tetrahydroxydiboron-promoted radical addition of internal alkynes followed by intramolecular oxidation of alcohol through 1,5-hydrogen atom transfer. Preliminary mechanistic studies showed that the process might be initiated through N,N-dimethylformamide-assisted homolytic cleavage of tetrahydroxydiboron. This process provides a convenient synthesis of fluoroalkyl-substituted alkenes with a pendant aldehyde or ketone moiety.

OXAZOLIDINONE HYDROXAMIC ACID COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS

This invention pertains generally to treating bacterial infections using organic compounds of Formula I. In certain aspects, the invention pertains to treating infections caused by Gram-negative bacteria. (I) wherein X, Y, R1, R2, R3, R4 and R5 and defined herein.

Support curvature and conformational freedom control chemical reactivity of immobilized species

We show that bimolecular reactions between species confined to the surfaces of nanoparticles can be manipulated by the nature of the linker, as well as by the curvature of the underlying particles.