85736-13-6

Basic information

• Product Name: 1-Penten-3-one, 1-(4-chlorophenyl)-4-hydroxy-4-methyl-, (1E)-
• CAS NO: 85736-13-6
• Molecular Formula: C12H13ClO2
• Molecular Weight: 224.687
• Mol File: 85736-13-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-Penten-3-one, 1-(4-chlorophenyl)-4-hydroxy-4-methyl-, (1E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Penten-3-one, 1-(4-chlorophenyl)-4-hydroxy-4-methyl-, (1E)-(85736-13-6)
• EPA Substance Registry System: 1-Penten-3-one, 1-(4-chlorophenyl)-4-hydroxy-4-methyl-, (1E)-(85736-13-6)

Safety Data

• Hazardous Substances Data: 85736-13-6(Hazardous Substances Data)

Upstream product

• 85736-16-9 2-(4-Chloro-phenyl)-5,5-dimethyl-dihydro-furan-3-one 
• 115-22-0 3-Hydroxy-3-methyl-2-butanone 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 290366-79-9 (R)-(-)-3-(4-chloro-phenyl)-4-nitro-butyric acid 
• 1092652-91-9 (E)-1-(4-chlorophenyl)-4-triethylsilyloxy-4-methylpent-1-en-3-one 
• 362494-81-3 methyl 4-(4-chlorophenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylate 
• 85736-16-9 2-(4-Chloro-phenyl)-5,5-dimethyl-dihydro-furan-3-one 
• 111277-17-9 1,2-Dibromo-1-(4-chloro-phenyl)-4-hydroxy-4-methyl-pentan-3-one 
• 111277-09-9 5-(p-chlorophenyl)-2,2-dimethyl-3(2H)-furanone 

Relevant articles and documents

α′-hydroxy Enones as Achiral Templates for Lewis Acid-Catalyzed Enantioselective Diels - Alder Reactions

α′-Hydroxy enones react with dienes in the presence of (S,S)-[Cu(tBu-box)](OTf)2 or (S,S)-[Cu(tBu-box)](SbF6)2 (2 to 10 mol %) to afford the corresponding Diels?Alder adducts in high yield and selectivity. Isomeric ratios (regioselectivity, endo/exo or cis/trans) of up to >99:1 and ee values of up to >99% are obtained. Significantly, difficult dienes such as isoprene, 2,3-dimethyl butadiene and piperylene behave satisfactorily. Subsequent oxidative cleavage of the ketol in the resulting cycloadducts by treatment with cerium ammonium nitrate (CAN) yields the corresponding enantiopure carboxylic acids. Alternatively, carbonyl addition and subsequent diol cleavage with CAN produces the corresponding ketone adducts. Copyright

Copper-catalyzed enantioselective conjugate addition of dialkylzinc reagents to α′-oxy enones

The copper-catalyzed enantioselective conjugate addition of dialkylzinc reagents to α'-oxy enones was investigated. Cu(OTf)2, ligand, and toluene were placed in a flame-dried Schlenk tube. the resulting mixture was stirred at room temperature f

Stereoelectronic Control of Intramolecular Michael Addition Reactions

Concepts of stereoelectronic control lead to the conclusion that the 5-endo-trig ring closure of (E)-2-methyl-3-oxo-5-phenylpent-4-en-2-ol should be disfavored.However, the acid-catalyzed ring closure in trifluoroacetic acid occurs readily, suggesting an