85738-40-5Relevant academic research and scientific papers
A scalable approach to diaminopyrazoles using flow chemistry
Wilson, Noel S.,Osuma, Augustine T.,Camp, Jennifer A.Van,Xu, Xiangdong
scheme or table, p. 4498 - 4501 (2012/10/08)
This Letter reports on how the combination of microwave and continuous flow chemistry facilitated the convenient preparation of aminopyrazoles from commercial aryl halides. The method was applied to a variety of substrates with good to excellent yields an
The Reaction of Phenylmalononitrile with Hydrazine. Synthesis and Properties of 3,5-Diamino-4-phenylpyrazole, 2-Amino-3-phenylpyrazolopyrimidine, and Related Compounds
Zvilichovsky, Gury,David, Mordechai
, p. 11 - 16 (2007/10/02)
3,5-Diamino-4-phenylpyrazole was prepared by the reaction of phenylmalononitrile with hydrazine hydrate.This hitherto unknown polyfunctional heterocycle reacted with acetylacetone, ethyl acetoacetate, 5-oxobutyraldehyde, malonaldehyde, diethyl (ethoxymeth
