857396-92-0Relevant academic research and scientific papers
Selective cleavage of the C-C bonds of aminoethyl groups, via a multistep pathway, by a pincer iridium complex
Zhang, Xiawei,Emge, Thomas J.,Ghosh, Rajshekhar,Goldman, Alan S.
, p. 8250 - 8251 (2005)
A pincer-ligated iridium complex is found to react with N-ethylamines, HN(Et)R (R = cyclohexyl, tert-butyl, ethyl), to give the corresponding iridium isocyanide complexes (PCP)Ir(CH3)(H)(CNR) (PCP = κ3-2,6-(tBu2PCH2)2C6H3). This novel, regioselective C-C bond cleavage reaction occurs readily under mild conditions (25-45 °C). The reaction is shown to proceed via initial dehydrogenation of the amine to give the corresponding imine (N-ethylidenealkylamine). The ethylidene sp2 C-H bond then undergoes addition to iridium, followed by methyl migration. Copyright
