857428-38-7Relevant academic research and scientific papers
Copper(II)-catalyzed synthesis of pyrimidines from propargylic alcohols and amidine: A propargylation-cyclization-oxidation tandem reaction
Lin, Min,Chen, Qing-Zhen,Zhu, Yu,Chen, Xin-Liang,Cai, Ji-Jun,Pan, Ying-Ming,Zhan, Zhuang-Ping
, p. 1179 - 1183 (2011)
A new approach to the tandem synthesis of 2,4-disubstituted or 2,4,6-trisubstituted pyrimidines from propargylic alcohols with amidine is described. This reaction is catalyzed by 20 mol% Cu(OTf)2 to give pyrimidines in moderate to good yields v
