857480-35-4

Usage

Uses

Used in Pharmaceutical Industry:
5-(3-bromophenyl)pentanoic acid is used as a building block for the synthesis of various drug molecules, contributing to the development of new pharmaceuticals.
Used in Medicinal Chemistry:
5-(3-bromophenyl)pentanoic acid is used as a reagent in organic chemical reactions, facilitating the synthesis of complex organic compounds for medicinal chemistry research.
Used in Drug Discovery Research:
5-(3-bromophenyl)pentanoic acid is used as a potential candidate in drug discovery research, aiding in the identification and development of novel therapeutic agents.

Upstream product

• 1180670-58-9 (4E)-5-(3-bromophenyl)pent-4-enoic acid 
• 17857-14-6 (3-carboxypropyl)(triphenyl)phosphonium bromide 
• 870679-57-5 5-(3-bromophenyl)pent-4-enoic acid 

Downstream Products

• 1798792-42-3 2-bromo-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-amine 
• 870679-50-8 ethyl 12-bromo-3-(2,4-dichlorophenyl)-3,4-diazatricyclo[8.4.0.0^2,6]tetradeca-1⁽¹⁴⁾,2⁽⁶⁾,4,10,12-pentaene-5-carboxylate 
• 870679-46-2 8-bromo-1-(2',4'-dichlorophenyl)-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxylic acid 

Relevant academic research and scientific papers

Discovery and Preclinical Characterization of BIIB091, a Reversible, Selective BTK Inhibitor for the Treatment of Multiple Sclerosis

Multiple Sclerosis is a chronic autoimmune neurodegenerative disorder of the central nervous system (CNS) that is characterized by inflammation, demyelination, and axonal injury leading to permeant disability. In the early stage of MS, inflammation is the

FUSED IMIDAZOPYRIDINES AS REVERSIBLE INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK)

The present invention relates to fused imidazo pyridine compounds of formula (I), and pharmaceutically acceptable compositions thereof, useful as BTK inhibitors.

BENZOAZEPINE ANALOGS AS INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE

Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their production and compounds of formula (I) for use in treating a disease responsive to the inhibition of Bruton's tyrosine.

BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY

The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.

BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY

The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.

Tricyclic fused pyrazoles with a 'Click' 1,2,3-triazole substituent in position 3 are nanomolar CB1 receptor ligands

Structural modification of the potent conformationally constrained tricyclic pyrazole CB1 ligand NESS0327 was achieved by replacing: (1) the chlorine substituent on the tricycle with a 3-fluoropropyl chain, and (2) the pyrazole 3-{[(piperidino)

HEPATITIS C VIRUS INHIBITORS

The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.

AMINO-PYRIDINE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS

The invention provides certain amino-pyridine-containing compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, and n are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase.

Tricyclic pyrazoles. 3. Synthesis, biological evaluation, and molecular modeling of analogues of the cannabinoid antagonist 8-chloro-1-(2′, 4′-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7] cyclohepta[1,2-c]pyrazole-3-carboxamide

A series of analogues of 8-chloro-1-(2′,4′-dichlorophenyl)-AT- piperidin-1-yl-1,4,5,6-tetrahydrobenzo-[6,7]cyclohepta[1,2-c] pyrazole-3-carboxamide 4a (NESS 0327) (Ruiu, S.; Pinna, G. A.; Marchese, G.; Mussinu, J. M.; Saba, P.; Tambaro, S.; Casti, P.; Var