85750-38-5Relevant articles and documents
Pharmaceutical compositions with antianginal activity
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, (2008/06/13)
The invention relates to pharmaceutical compositions possessing valuable antianginal activity. These compositions show higher activity and more favorable therapeutic indices than the reference compound Prenylamine. Preparation of different kinds of pharmaceutical compositions, such as tablets, dragees, capsules and injectable solutions, containing compounds of general formula (I) STR1 or their acid addition salts as active ingredients, is disclosed, wherein in formula (I) R is phenyl or 4-chlorophenyl; R1 and R2 each represent hydrogen, methyl or isopropyl; R3 and R4 are hydrogen, or together form a chemical bond; n is an integer from 4 to 6; A means trimethylene, if n is 4 or 6; or ethylene, if n is 5.