857581-46-5Relevant academic research and scientific papers
PhI(OCOCF3)2-mediated intramolecular oxidative N-N bond formation: Metal-free synthesis of 1,2,4-triazolo[1,5-a]pyridines
Zheng, Zisheng,Ma, Shuangyu,Tang, Linlin,Zhang-Negrerie, Daisy,Du, Yunfei,Zhao, Kang
, p. 4687 - 4693 (2014)
The biologically important 1,2,4-triazolo[1,5-a]pyridines were readily synthesized from N-(pyridin-2-yl)benzimidamides via phenyliodine bis(trifluoroacetate)-mediated intramolecular annulation. This novel strategy allows for the convenient construction of a 1,2,4-triazolo[1,5-a]pyridine skeleton through direct metal-free oxidative N-N bond formation, featuring a short reaction time and high reaction yields.
