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857637-03-7

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857637-03-7 Usage

General Description

[1-(2-AMINOETHYL)PIPERIDIN-3-YL]METHANOL is a chemical compound with a complex structure, consisting of a piperidine ring attached to an aminoethyl group and a methanol molecule. It is used in pharmaceutical research and drug development due to its potential biological and therapeutic properties. [1-(2-AMINOETHYL)PIPERIDIN-3-YL]METHANOL may have a range of applications, including as a building block for the synthesis of new drugs, or as a tool in the study of biological systems. The presence of both amine and alcohol functional groups in its structure suggests that it may have interactions with biological targets such as proteins or enzymes, making it a molecule of interest for further investigation in medicinal chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 857637-03-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,7,6,3 and 7 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 857637-03:
(8*8)+(7*5)+(6*7)+(5*6)+(4*3)+(3*7)+(2*0)+(1*3)=207
207 % 10 = 7
So 857637-03-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H18N2O/c9-3-5-10-4-1-2-8(6-10)7-11/h8,11H,1-7,9H2

857637-03-7 Well-known Company Product Price

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  • Aldrich

  • (CBR01408)  [1-(2-Aminoethyl)piperidin-3-yl]methanol  AldrichCPR

  • 857637-03-7

  • CBR01408-1G

  • 2,255.76CNY

  • Detail

857637-03-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name [1-(2-aminoethyl)piperidin-3-yl]methanol

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

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More Details:857637-03-7 SDS

857637-03-7Downstream Products

857637-03-7Relevant articles and documents

Development of nonsymmetrical 1,4-disubstituted anthraquinones that are potently active against cisplatin-resistant ovarian cancer cells

Pors, Klaus,Plumb, Jane A.,Brown, Robert,Teesdale-Spittle, Paul,Searcey, Mark,Smith, Paul J.,Patterson, Laurence H.

, p. 6690 - 6695 (2007/10/03)

A novel series of 1,4-disubstituted aminoanthraquinones were prepared by ipso-displacement of 1,4-difluoro-5,8-dihydroxyanthraquinones by hydroxylated piperidinyl- or pyrrolidinylalkyl-amino side chains. One aminoanthraquinone (13) was further derivatized to a chloropropyl-amino analogue by treatment with triphenylphosphine-carbon tetrachloride. The compounds were evaluated in the A2780 ovarian cancer cell line and its cisplatin-resistant variants (A2780/cp70 and A2780/MCP1). The novel anthraquinones were shown to possess up to 5-fold increased potency against the cisplatin-resistant cells compared to the wild-type cells. Growth curve analysis of the hydroxyethylaminoanthraquinone 8 in the osteosarcoma cell line U-2 OS showed that the cell cycle is not frozen, rather there is a late cell cycle arrest consistent with the action of a DNA-damaging topoisomerase II inhibitor. Accumulative apoptotic events, using time lapse photography, indicate that 8 is capable of fully engaging cell cycle arrest pathways in G2 in the absence of early apoptotic commitment. 8 and its chloropropyl analogue 13 retained significant activity against human A2780/cp70 xenografted tumors in mice.

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