857653-94-2 Usage
Uses
Used in Pharmaceutical Applications:
[3-(4-pyridinyl)-1,2,4-oxadiazol-5-yl]methanol (SALTDATA: FREE) is used as a pharmaceutical agent for its potential to modulate specific protein targets. Its unique structure allows it to interact with biopolymers and macromolecules, making it a promising candidate for the development of new therapeutic strategies against various diseases and disorders.
Used in Research Applications:
In the research industry, [3-(4-pyridinyl)-1,2,4-oxadiazol-5-yl]methanol (SALTDATA: FREE) is utilized as a research tool to study its potential biological activity and explore its applications in the treatment of various diseases and disorders. Its unique chemical structure provides researchers with valuable insights into the compound's interactions with specific protein targets, contributing to the advancement of medical knowledge and the development of novel therapeutic approaches.
Safety and Handling:
It is crucial to handle and store [3-(4-pyridinyl)-1,2,4-oxadiazol-5-yl]methanol (SALTDATA: FREE) with care, adhering to standard safety protocols and practices. This ensures the safety of individuals working with the compound and minimizes the risk of adverse effects or accidents during its use in pharmaceutical and research applications.
Check Digit Verification of cas no
The CAS Registry Mumber 857653-94-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,7,6,5 and 3 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 857653-94:
(8*8)+(7*5)+(6*7)+(5*6)+(4*5)+(3*3)+(2*9)+(1*4)=222
222 % 10 = 2
So 857653-94-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H7N3O2/c12-5-7-10-8(11-13-7)6-1-3-9-4-2-6/h1-4,12H,5H2
857653-94-2Relevant academic research and scientific papers
One-step protection-free synthesis of 3-aryl-5-hydroxyalkyl-1,2,4- oxadiazoles as building blocks
Neves Filho, Ricardo A. W.,Da Silva-Alves, Diana C. B.,Dos Anjos, Janaina V.,Srivastava, Rajendra M.
supporting information, p. 2596 - 2602 (2013/07/26)
A simple and straightforward synthesis of 3-aryl-5-hydroxyalkyl-1,2,4- oxadiazoles is described. The reaction among arylamidoximes, ethyl glycolate or ethyl lactate, and potassium carbonate in refluxing toluene afforded the desired 1,2,4-oxadiazoles in moderate to good yields. The synthesis has been accomplished in a single step, avoiding protection-deprotection protocols. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications to view the free supplemental file.
HETEROCYCLIC DERIVATIVES AS GPCR RECEPTOR AGONISTS
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Page/Page column 26-27, (2008/06/13)
Compounds of Formula (I), R1-A-V-B-R2; or pharmaceutically acceptable salts thereof, are agonists of GPR116 and are useful as regulators of satiety, e.g. for the treatment of obesity, and for the treatment of diabetes.
