857732-46-8Relevant academic research and scientific papers
Enantiospecific synthesis of the heparanase inhibitor (+)-trachyspic acid and stereoisomers from a common precursor
Zammit, Steven C.,Ferro, Vito,Hammond, Edward,Rizzacasa, Mark A.
, p. 2826 - 2834 (2008/03/14)
The total synthesis of natural (+)-trachyspic acid and its enantiomer is described starting from a common 2-deoxy-d-ribose derivative. The synthesis of the corresponding C3 epimers from the same starting material is also described. Each stereoisomer was a
Enantiospecific synthesis of (-)-trachyspic acid
Zammit, Steven C.,White, Jonathan M.,Rizzacasa, Mark A.
, p. 2073 - 2074 (2007/10/03)
The enantiospecific synthesis of (-)-trachyspic acid is presented. The D-oxyribose derived alcohol was oxidized in one step to the acid and esterification with allyl alcohol provided ester. Alkylation of the anion derived from dimethyl malonate with nonyl
