857896-74-3Relevant academic research and scientific papers
INHALED CARBAPROSTACYCLIN AND PROSTACYCLIN PRODRUGS FOR THE TREATMENT OF PULMONARY ARTERIAL HYPERTENSION
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Page/Page column 58-59, (2010/01/07)
Phenylphosphonate prodrugs comprising one or more prostacyclins are provided for the treatment of pulmonary arterial hypertension. Also provided are inhalable formulations of the prodrugs for delivery by aerosolization or dry powder. The compounds and for
BENZYLPHOSPHATE AND SUBSTITUTED BENZYLPHOSPHATE PRODRUGS FOR TRE TREATMENT OF PULMONARY INFLAMMATION
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Page/Page column 13; 36-37, (2010/02/12)
A prodrug of a corticosteroid, lidocaine or related local anesthetic composition for formulation for delivery by aerosolization to inhibit inflammation in asthmatic lungs is described. The prodrug is preferably formulated in a 5 ml solution of a quarter normal saline having pH between 5.0 and 7.0 for the treatment of respiratory tract inflammation by an aerosol having mass medium average diameter predominantly between 1 to 5 μ produced by nebulization or dry powder inhaler.
