857941-07-2Relevant academic research and scientific papers
Polyamine-vectored iron chelators: The role of charge
Bergeron, Raymond J.,Bharti, Neelam,Wiegand, Jan,McManis, James S.,Yao, Hua,Prokai, Laszlo
, p. 4120 - 4137 (2007/10/03)
The utility of polyamines as vectors for the intracellular transport of iron chelators is further described. Consistent with earlier results with polyamine analogues, these studies underscore the importance of charge in the design of polyamine-vectored ch
POLYAMINE-METAL CHELATOR CONJUGATES
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Page/Page column 45, (2008/06/13)
Many metal chelators have polar or charged functional groups, which render them difficult to transport across a cell membrane. Polyamine-metal chelator conjugates of the invention are compounds comprising a first moiety which is a metal chelator and a sec
