85796-63-0Relevant academic research and scientific papers
α,α′-C-H Bond Difunctionalization of Unprotected Alicyclic Amines
Valles, Daniel A.,Dutta, Subhradeep,Paul, Anirudra,Abboud, Khalil A.,Ghiviriga, Ion,Seidel, Daniel
supporting information, p. 6367 - 6371 (2021/08/18)
A simple one-pot procedure enables the sequential, regioselective, and diastereoselective introduction of the same or two different substituents to the α- and α′-positions of unprotected azacycles. Aryl, alkyl, and alkenyl substituents are introduced via their corresponding organolithium compounds. The scope of this transformation includes pyrrolidines, piperidines, azepanes, and piperazines.
Silver(I)-catalyzed Oxidation of Cyclic Secondary Amines with Peroxodisulphate
Ogawa, Keiichiro,Nomura, Yujiro,Takeuchi, Yoshito,Tomoda, Shuji
, p. 3031 - 3036 (2007/10/02)
Oxidation of Piperidines, pyrrolidine, azetidine, perhydroazepine, and perhydroazocine with aqueous alkaline sodium peroxodisulphate in the presence of silver nitrate gave 1,1'-bipiperidines, a trimer of 1-pyrroline, 1,1'-biazetidine, 1,1'-biperhydroazepine together with 1-formylperhydroazepine, and 1-formylperhydroazocine, respectively.
