858002-39-8Relevant academic research and scientific papers
Antioxidant and antitumor activities of 4-arylcoumarins and 4-aryl-3,4-dihydrocoumarins
Zhang, Keyun,Ding, Weixian,Sun, Jie,Zhang, Bin,Lu, Fujiao,Lai, Ren,Zou, Yong,Yedid, Gabriel
supporting information, p. 203 - 210 (2015/02/19)
Five 4-arylcoumarins (1c-g) and twelve 3,4-dihydro-4-arylcoumarins (2a-l) were synthesized and tested for antioxidant activity, antitumor activity, toxicity and structure-activity relationships analysis. 4-Arylcoumarins and 3,4-dihydro-4-arylcoumarins tha
Microwave-promoted automated synthesis of a coumarin library
Katkevi?s,Kontijevskis,Mutule,Sūna
, p. 151 - 159 (2008/12/20)
A 30-membered library of coumarins has been synthesized in a microwave-assisted Pechmann reaction using neat trifluoroacetic acid both as an acidic reagent and a reaction medium. Alternatively, polymer-supported sulfonic acid Amberlyst-15 could also be employed to facilitate the formation of coumarins. The use of a specially-built microwave synthesizer with liquid handling tools rendered the automated synthesis of a coumarin library feasible.
