858005-68-2

Upstream product

• 6346-09-4 4-aminobutyrylaldehyde diethylacetal 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 1443054-31-6 4-methyl-N-(3-methylbut-2-en-1-yl)-N-(4-oxobutyl)benzenesulfonamide 
• 1443054-40-7 (E)-4-methyl-N-(4-oxobutyl)-N-(3-phenylbut-2-en-1-yl)benzenesulfonamide 

Relevant academic research and scientific papers

Synthesis of 1-(arenesulfonyl)-2-arylpyrrolidines by reaction of N-(4,4-diethoxybutyl)-4-methylbenzene-sulfonamide with phenols

New 1-(arenesulfonyl)-2-arylpyrrolidines were synthesized by reactions of several phenols with N-(4,4-diethoxybutyl)-4-methylbenzenesulfonamide in the presence of trifluoroacetic acid.

One-pot imination / Arbuzov reaction of 4-aminobutanal derivatives: Synthesis of 2-phosphorylpyrrolidines and evaluation of anticancer activity

A novel one-pot method for the preparation of N-substituted 2-phopshorylpyrrolidines from readily available 4,4-diethoxybutan-1-amine derivatives and P (III) acid chlorides is described. The presented method benefits from simple reaction and work-up proce

Acid-catalyzed reaction of phenols with N-(4,4-diethoxybutyl)sulfonamides – a new method for the synthesis of 2-aryl-1-sulfonylpyrrolidines

[Figure not available: see fulltext.]We have developed a new method for the synthesis of 2-aryl-1-sulfonylpyrrolidines on the basis of reactions between various phenols and N-(4,4-diethoxybutyl)sulfonamides in the presence of trifluoroacetic acid. The str

Acid-catalyzed intramolecular cyclization of N-(4,4-diethoxybutyl)sulfonamides as a novel approach to the 1-sulfonyl-2-arylpyrrolidines

Herein we report our studies on the acid-catalyzed cyclisation of N-(4,4-diethoxybutyl)sulfonamides at the presence of polyatomic phenols as an efficient one-pot approach to the synthesis of 1-sulfonyl-2-arylpyrrolidines from the acyclic precursors.

Enantioselective intramolecular aldehyde α-alkylation with simple olefins: Direct access to homo-ene products

A highly selective method for the synthesis of asymmetrically substituted carbocycles and heterocycles from unactivated aldehyde-olefin precursors has been achieved via enantioselective SOMO-catalysis. Addition of a catalytically generated enamine radical cation across a pendent olefin serves to establish a general asymmetric strategy toward the production of a wide range of formyl-substituted rings with alkene transposition. Conceptually, this novel mechanism allows direct access to "homo-ene"-type products.

Triflic acid-mediated phenylation of N-acylaminoalkyl diethylacetals and N-acyl-2-phenyl cyclic amides

The reaction of N-acylaminoalkyl diethylacetals with triflic acid in benzene gave N-acylamino-diphenylalkyls. The proposed intermediates are the N-acyl-2-phenyl cyclic amides, which themselves are similarly converted to N-acylamino-diphenylalkyls.