858036-54-1Relevant academic research and scientific papers
Platinum-catalyzed intermolecular hydroamination of vinyl arenes with carboxamides
Qian, Hua,Widenhoefer, Ross A.
, p. 2635 - 2638 (2005)
(Chemical Equation Presented) Reaction of benzamide with 4-methylstyrene catalyzed by a 1:2 mixture of [PtCl2(H2C=CH 2)]2 and P(4-C6H4CF 3)3 (5 mol %) in mesitylene at 140 °C for 24 h led to the isolation of N-(1-p-tolylethyl)benzamide in 85% yield. Electron-rich, electron-poor, and hindered vinyl arenes underwent Markovnikov hydroamination with a range of carboxamides and amide derivatives in moderate to good yield with excellent regioselectivity.
