858108-98-2

Upstream product

• 34637-22-4 3-[(N-benzyloxycarbonyl)amino]propanol 
• 51532-75-3 3,4,6-tri-O-benzyl-1,2-O-(1-methoxyethylidene)-α-D-glucopyranose 
• 858108-96-0 N-(benzyloxycarbonyl)aminopropyl 3,4,6-tri-O-benzyl-β-D-glucopyranoside 

Downstream Products

• 858109-02-1 N-(benzyloxycarbonyl)aminopropyl 2-acetamido-3,4-di-O-benzyl-2-deoxy-β-D-mannopyranoside 
• 858109-00-9 N-(benzyloxycarbonyl)aminopropyl 2-acetamido-3,4,6-tri-O-benzyl-2-deoxy-β-D-mannopyranoside 
• 858109-06-5 [N-(benzyloxycarbonyl)aminopropyl (2-acetamido-3,4-di-O-benzyl-2-deoxy-β-D-mannopyranosidyl)]methyl C-(2-acetamido-3,4-di-O-benzyl-2-deoxy-α-D-mannopyranosyl)methanephosphonate 
• 952139-86-5 [N-(benzyloxycarbonyl)aminopropyl (2-acetamido-3,4-di-O-benzyl-2-deoxy-β-D-mannopyranosidyl)]methyl C-(2-acetamido-6-O-acetyl-3,4-di-O-benzyl-2-deoxy-α-D-mannopyranosyl)methanephosphonate 
• 858109-04-3 [N-(benzyloxycarbonyl)aminopropyl (2-acetamido-3,4-di-O-benzyl-2-deoxy-β-D-mannopyranosidyl)]methyl C-(2-acetamido-3,4,6-tri-O-benzyl-2-deoxy-α-D-mannopyranosyl)methanephosphonate 

Relevant academic research and scientific papers

Synthesis and biological evaluation of phosphono analogues of capsular polysaccharide fragments from Neisseria meningitidis A

Neisseria meningitidis type A (MenA) is a Gram-negative encapsulated bacterium that may cause explosive epidemics of meningitis, especially in the sub-Saharan region of Africa. The development and manufacture of an efficient glycoconjugate vaccine against

Synthesis of the phosphono analogue of the dimeric subunit of Neisseria meningitidis type A capsular polysaccharide

The development of a glycoconjugate vaccine against N. meningitidis type A bacterium is greatly hampered by the chemical lability of the phosphodiester bridges joining the N-acetyl mannosamine repeating units of its capsular polysaccharide. We describe th