858121-94-5

Basic information

• Product Name: 4-Bromomethyl-1,1-difluoro-cyclohexane
• Synonyms: 4-Bromomethyl-1,1-difluoro-cyclohexane
• CAS NO: 858121-94-5
• Molecular Formula: C₇H₁₁BrF₂
• Molecular Weight: 213.0630464
• Mol File: 858121-94-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 195℃
• Flash Point: 72℃
• Appearance: /
• Density: 1.41
• CAS DataBase Reference: 4-Bromomethyl-1,1-difluoro-cyclohexane(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromomethyl-1,1-difluoro-cyclohexane(858121-94-5)
• EPA Substance Registry System: 4-Bromomethyl-1,1-difluoro-cyclohexane(858121-94-5)

Safety Data

• Hazardous Substances Data: 858121-94-5(Hazardous Substances Data)

Usage

General Description

4-Bromomethyl-1,1-difluoro-cyclohexane is a chemical compound consisting of a cyclohexane ring with a bromomethyl group and two difluoromethyl groups attached to it. It is used as a building block in the synthesis of various organic compounds and can serve as a precursor for the preparation of pharmaceuticals and agrochemicals. This chemical may also have applications in the field of materials science and can be used as a reagent in organic synthesis. Additionally, it is important to handle this compound with care, as it may pose health and environmental hazards due to its reactive nature and potential toxicity.

Upstream product

• 178310-99-1 (4,4-difluorocyclohexyl)methyl 4-methylbenzenesulfonate 
• 178312-48-6 (4,4-difluorocyclohexyl)methanol 

Downstream Products

• 1384875-15-3 N-[(4,4-difluorocyclohexyl)methyl]-5-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-5,8-diazaspiro[2.5]octane-8-sulfonamide 
• 1384875-16-4 N-[(4,4-difluorocyclohexyl)methyl]-N-ethyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-5,8-diazaspiro[2.5]octane-8-sulfonamide 
• 1384875-17-5 N,N-bis[(4,4-difluorocyclohexyl)methyl]-5-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-5,8-diazaspiro[2.5]octane-8-sulfonamide 
• 949033-38-9 C₁₁H₁₉F₂NO₂ 
• 1122648-78-5 4-(azidomethyl)-1,1-difluorocyclohexane 

Relevant articles and documents

Substituted Pyrrolidine Amides II

The invention relates to compounds according to general formula (I), which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.

ISOXAZOL-3(2H)-ONE ANALOGS AS THERAPEUTIC AGENTS

or a pharmaceutically suitable salt thereof, wherein, R1 and R2 independently are hydrogen, deuterium, aryl, hetero aryl, C1-C8 alkyl, optionally being substituted with one or more substituents independently being R3,R3 is an aryl, hetero aryl, fluorine(s), a C1-C6 alkyl containing one or more fluorine, a C1-C6 alkyl containing one or more deuterium, a C1-C6 alkyl containing hydroxy, the aryl and heteroaryl optionally being substituted with one or more halogen, a fluorinated alkoxy, a fluorinated alkyl, a sulfonyl, one or more deuterium, a C1-6 alkyl, a C1-6 alkoxy, a nitrile,or R3 is a C1-6 alkyl optionally substituted with one or more of the following groups: COOR4, OCOR4, CONR5R6, NR5COR6, OR4;wherein, R4 is a C1-10 alkyl optionally substituted with one or more fluorine, deuterium, alkoxy, arylcarboxylate, alkyl carboxylate;R5 and R6 are independently selected from hydrogen, alkyl or they may together form a 4-8 membered carbon ring;or R1 and R2 form a 3-10 membered carbon ring optionally comprising O or N and optionally substituted with a C1-10 alkyl or aryl, hetero aryl optionally substituted with R3.