858124-04-6Relevant articles and documents
Angiogenesis inhibitors identified by cell-based high-throughput screening: Synthesis, structure-activity relationships and biological evaluation of 3-[(E)-styryl]benzamides that specifically inhibit endothelial cell proliferation
Hada, Kihito,Suda, Atsushi,Asoh, Kohsuke,Tsukuda, Takuo,Hasegawa, Masami,Sato, Yasuko,Ogawa, Kotaro,Kuramoto, Shino,Aoki, Yuko,Shimma, Nobuo,Ishikawa, Tsutomu,Koyano, Hiroshi
experimental part, p. 1442 - 1460 (2012/04/17)
Proliferation of endothelial cells is critical for angiogenesis. We report orally available, in vivo active antiangiogenic agents which specifically inhibit endothelial cell proliferation. After identifying human umbilical vein endothelial cell (HUVEC) pr
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Page/Page column 40-41, (2010/11/23)
To provide compounds which have high angiogenesis inhibiting activity, and are useful as agents for effective treatment and prevention of diseases involving pathologic angiogenesis, for example, cancer and cancer metastasis, methods for producing the comp