85814-66-0

Basic information

• Product Name: 1-cyclohexyl-2-nitro-propan-1-one
• Synonyms: 1-cyclohexyl-2-nitro-propan-1-one
• CAS NO: 85814-66-0
• Molecular Weight: 185.223
• Mol File: 85814-66-0.mol

Chemical Properties

• CAS DataBase Reference: 1-cyclohexyl-2-nitro-propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-cyclohexyl-2-nitro-propan-1-one(85814-66-0)
• EPA Substance Registry System: 1-cyclohexyl-2-nitro-propan-1-one(85814-66-0)

Safety Data

• Hazardous Substances Data: 85814-66-0(Hazardous Substances Data)

Upstream product

• 87377-90-0 1-cyclohexyl-2-nitropropan-1-ol 
• 79-24-3 Nitroethane 
• 2043-61-0 cyclohexanecarbaldehyde 

Downstream Products

• 85814-75-1 C₁₆H₂₃N₃O₄S 
• 86208-68-6 C₉H₁₅⁽²⁾HO 
• 85814-80-8 C₁₆H₂₄N₂O₂S 
• 86208-72-2 C₁₆H₂₃⁽²⁾HN₂O₂S 

Relevant articles and documents

A one pot, solvent-free synthesis of acyclic α-nitro ketones through the nitroaldol reaction

Acyclic α-nitro ketones are easily obtained in one pot, through a solvent-free procedure by nitroaldol (Henry) reaction on neutral alumina, then in situ oxidation of the nitroalkanol using wet alumina supported chromium(VI) oxide.

Asymmetric Michael addition of α-nitro-ketones using catalytic peptides

Peptide-based catalysts have been developed that promote the asymmetric Michael addition of nitroalkanes. The most effective peptides contain a β-turn structural element as well as a basic histidine and an arylsulfonamide-protected arginine. Excellent yields with enantioselectivities of up to 74% ee have been observed.