85828-09-7

Basic information

• Product Name: (S)-(-)-1-(2-FURYL)ETHANOL
• Synonyms: (S)-(-)-1-(2-FURYL)ETHANOL;(S)-1-(2-FURYL)ETHANOL;S(-)-2-FURYL METHYL CARBINOL;S(-)-ALPHA-METHYLFURAN-2-METHANOL;(S)-(-)-1-(2-FURYL)ETHANOL 99%;(s)-(-)-α-methylfuran-2-methanol;(S)-1-(2-Furyl)ethanol(stabilized with hydroquinone);(S)-(-)-α-Methylfuran-2-methanol, (S)-(-)-2-Furyl methyl carbinol
• CAS NO: 85828-09-7
• Molecular Formula: C₈H₁₀O₃
• Molecular Weight: 112.13
• Product Categories: Alcohols, Hydroxy Esters and Derivatives;Chiral Compounds
• Mol File: 85828-09-7.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 60-61 °C8 mm Hg(lit.)
• Flash Point: 110 °C
• Appearance: clear yellow liquid
• Density: 1.078 g/mL at 20 °C(lit.)
• Refractive Index: n20/D 1.479
• Storage Temp.: −20°C
• BRN: 4665087
• CAS DataBase Reference: (S)-(-)-1-(2-FURYL)ETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(-)-1-(2-FURYL)ETHANOL(85828-09-7)
• EPA Substance Registry System: (S)-(-)-1-(2-FURYL)ETHANOL(85828-09-7)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 85828-09-7(Hazardous Substances Data)

Usage

Chemical Properties

clear yellow liquid

Upstream product

• 1192-62-7 1-(2-furyl)-1-ethanone 
• 64-19-7 acetic acid 
• 22426-24-0 (R/S)-1-(2-furyl)ethyl acetate 
• 4208-64-4 1-(2-furyl)ethanol 
• 108-05-4 vinyl acetate 
• 108-22-5 Isopropenyl acetate 
• 41019-60-7 1-(furan-2-yl)vinyl acetate 
• 108-24-7 acetic anhydride 
• 1207204-70-3 (S)-1-(furan-3-yl)ethan-1-ol 

Downstream Products

• 14031-88-0 (S)-O-Acetyllactic acid Methyl Ester 

Relevant articles and documents

Practical access to (S)-heterocyclic aromatic acetates via CAL-B/Na2CO3-deacylation and Mitsunobu reaction protocol

Herein, we report the preparation of enantiomerically pure forms of 2,3-dihydrobenzofuran-3-ol (1), chroman-4-ol (2), thiochroman-4-ol (3), 1-(furan-2-yl) ethanol (5) and 1-(thiophen-2-yl) ethanol (6), through a kinetic resolution catalysed by Candida antarctica lipase B/Na2CO3 hydrolysis sequence in organic media. The (R)-furnished alcohols and the (S)-remained acetates are recovered enantiopures (ee?>99%, E???200, Conv = 50%). Those ideal enzymatic kinetic resolution (EKRs) are well incorporated to the Mitsunobu inversion protocol in a one pot procedure to give (S)-heterocyclic acetates (1a–3a) in good to high enantiomeric excess (88%–92% ee). Whilst, the (S)-heteroaromatic acetates (5a and 6a) are given with moderate enantiomeric excess (51%–62% ee). All the (S)-acetates are given in good isolated chemical yields (>80%) allowing to overcome the maximum of 50% yield which could be usually reached in a regular kinetic resolution processes.

Lipase-catalysed kinetic resolutions of secondary alcohols in pressurised liquid hydrofluorocarbons

Three model secondary alcohols have been subjected to enzymatic kinetic resolution using three common lipases and a typical acyl donor. The resolutions were performed in two pressurised low-boiling hydrofluorocarbons, which are novel media for enzymatic reactions, and five conventional organic solvents. In general, higher yields, ee's and rates of reaction were observed in the hydrofluorocarbons.

A divergent synthesis of uncommon sugars from furanaldehyde

A practical synthetic strategy has been developed for producing uncommon sugars. This method employed kinetic enzymatic resolution of 1-(2-furyl)ethanol, and followed by NBS-mediated Achmatowicz rearrangement to construct α,β-unsaturated lactones. After further derivatization, five representative uncommon sugar units were successfully synthesized. Georg Thieme Verlag Stuttgart.